UnderDeveloped API’s : Treatment of Schizophrenia
CAS NO. 133454-47-4
Therapeutic Class: Treatment of schizophrenia
Pharmacopoeia compliance: USP/EP
Iloperidone is used for the treatment of schizophrenia. In a 2013 study in a comparison of 15 antipsychotic drugs in effectivity in treating schizophrenic symptoms, iloperidone demonstrated mild effectiveness. As effective as lurasidone and 13-15% less effective than ziprasidone, chlorpromazine and asenapine.
Iloperidone is a monoamine directed towards acting upon and antagonizing specific neurotransmitters, particularly multiple dopamine and serotonin receptor subtypes. It is considered an ‘atypical’ antipsychotic because it displays serotonin receptor antagonism, similar to other atypical antipsychotics. The older typical antipsychotics are primarily dopamine antagonists.