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UnderDeveloped API’s

Anti-DiabeticTreatment of SchizophreniaOpioid AnalgesicVasodilator


CAS NO. 29094-61-9
Therapeutic Class: Anti-Diabetic
Pharmacopoeia compliance: USP/BP

Glipizide is an oral rapid and short-acting anti-diabetic medication from the sulfonylurea class. It is classified as a second-generation sulfonylurea, which means that it undergoes enterohepatic circulation. Second-generation sulfonylureas are both more potent and have shorter half-lives than the first-generation sulfonylureas.



CAS NO. 133454-47-4
Therapeutic Class: Treatment of schizophrenia
Pharmacopoeia compliance: USP/EP

Iloperidone is used for the treatment of schizophrenia. In a 2013 study in a comparison of 15 antipsychotic drugs in effectivity in treating schizophrenic symptoms, iloperidone demonstrated mild effectiveness. As effective as lurasidone and 13-15% less effective than ziprasidone,  chlorpromazine and asenapine.

Iloperidone is a monoamine directed towards acting upon and antagonizing specific neurotransmitters, particularly multiple dopamine and serotonin receptor subtypes. It is considered an ‘atypical’ antipsychotic because it displays serotonin receptor antagonism, similar to other atypical antipsychotics. The older typical antipsychotics are primarily dopamine antagonists.


CAS NO. 175591-09-0
Therapeutic Class: Opioid analgesic
Pharmacopoeia compliance: USP/IP

Tapentadol is used for the treatment of moderate to severe pain for both acute (following injury, surgery etc.) and chronic musculoskeletal pain. It is also specifically indicated for controlling the pain of diabetic neuropathy when around-the-clock opioid medication is required.

Its general potency is somewhere between that of tramadol and morphine with an analgesic efficacy comparable to that of oxycodone despite a lower incidence of side effects.

Tapentadol is Pregnancy Category C. There are no adequate and well-controlled studies of tapentadol in pregnant women and tapentadol is not recommended for use in women during and immediately prior to labor and delivery


CAS NO. 209-443-6
Therapeutic Class: Vasodilator
Pharmacopoeia compliance: USP

Isoxsuprine it is used in humans for treatment of premature labor, i.e. a tocolytic and as a vasodilator for the treatment of cerebral vascular insufficiency, Raynaud’s phenomenon and other conditions.